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Cytogenetic Analysis for Clonal Cell Rearrangement (Bone Marrow)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic changes in your bone marrow cells that may indicate conditions like leukemia or other blood disorders.

Quick summary

["A screening to detect abnormal genetic patterns in your blood cells."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104273-8
Short code
Clonal cells rearrange/Cells NFr Spec
Synonyms
Clonal cells rearrange/Cells NFr Spec
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms of blood disorders, such as unexplained fatigue, frequent infections, or unusual bruising. It’s also used in monitoring known conditions like cancer or blood diseases to check for changes in your cells.

What to Expect Before the Test

You’ll likely have a small needle inserted into your arm or leg to draw blood, or a needle inserted into your hip bone to collect bone marrow. The procedure is usually quick and may cause mild discomfort.

What the Test Results Mean

Results show whether your bone marrow cells have genetic rearrangements that could suggest abnormal growth. If abnormalities are found, further testing may be needed to determine the cause.

Common Conditions Monitored

This test helps diagnose or monitor conditions like chronic myeloid leukemia (CML), acute myeloid leukemia (AML), or other hematologic malignancies where specific genetic mutations are present.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Clonal Cells Screening

Frequently asked questions

What does a positive result mean?
A positive result means your bone marrow cells show genetic rearrangements that may suggest an underlying blood disorder or cancer. Your doctor will discuss next steps, which could include additional tests or treatment planning.
How often should I get this test?
Frequency depends on your medical history and treatment plan. Your doctor will determine how often you need retests, especially if you’re undergoing treatment for a blood-related condition.
Can I eat or drink before this test?
For blood tests, you can eat and drink normally. For bone marrow tests, follow your doctor’s instructions, as fasting may not apply, but hydration is still important.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy