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Clonidine concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of clonidine, a medication used to treat high blood pressure or withdrawal symptoms from certain drugs, in your blood.

Quick summary

["Clonidine levels help monitor drug effectiveness and side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73032-5
Short code
cloNIDine (neut) IgG SerPl Ql FC
Synonyms
cloNIDine (neut) IgG SerPl Ql FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking clonidine to check if the medication is working properly or if you’re experiencing unusual side effects. It might also be used to assess drug levels in cases of suspected overdose or improper dosing.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The process is quick and typically done in a lab or clinic setting.

What the Test Results Mean

Results are interpreted by your healthcare provider based on your medical history, symptoms, and other factors. Abnormal levels may indicate ineffective treatment, toxicity, or other health concerns.

Common Uses and Considerations

Clonidine is often monitored in patients with hypertension, opioid withdrawal, or certain neurological conditions. If you’re on this medication, discuss any changes in symptoms or side effects with your doctor before testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clonidine levels can vary based on factors like dosage, time since last dose, metabolism, and underlying health conditions. High levels may cause dizziness, dry mouth, or low blood pressure, while very low levels might suggest insufficient medication.

Short name

Plasma Clonidine Level

Frequently asked questions

What does a ‘high’ or ‘low’ clonidine level mean?
High levels could signal overdose, improper dosing, or liver/kidney issues affecting metabolism. Low levels may mean the medication isn’t working as intended. Your doctor will assess this in context of your symptoms and treatment plan.
How long does it take to get results?
Results are usually available within 1–3 business days, depending on lab processing times. Your provider will contact you once they’re ready.
Can I eat or drink before this test?
No special diet is required, but avoid caffeine or alcohol before the draw if instructed by your provider, as they may affect blood chemistry.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy