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Total Cholesterol (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood, which includes both the cholesterol your body makes and the cholesterol you get from foods.

Quick summary

["Cholesterol levels help assess your risk for heart disease and other health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39598-8
Short code
C lunata IgE/IgE total %
Synonyms
C lunata IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does Cholesterol Do in Your Body?

Cholesterol is a type of fat that your body needs to function properly. It helps form cell membranes, produces hormones, and aids in the digestion of fats. However, having too much cholesterol in your blood can lead to plaque buildup in your arteries, increasing the risk of heart disease or stroke.

Why Is This Test Important?

Measuring total cholesterol helps healthcare providers assess your cardiovascular health. High cholesterol levels may require lifestyle changes or medication to manage your risk.

How Is This Test Performed?

A blood sample is taken from a vein in your arm, usually in a clinic or lab setting. The sample is then sent for analysis to determine your total cholesterol level.

What Are Common Reference Ranges?

While exact reference ranges can vary by lab, typical guidelines suggest desirable cholesterol levels are below a certain threshold, often categorized as low, borderline-high, or high depending on overall cardiovascular risk factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Cholesterol

Frequently asked questions

What causes cholesterol levels to change?
Cholesterol levels can be influenced by diet (e.g., high intake of saturated fats), genetics, weight, physical activity, and certain medical conditions. Lifestyle factors like smoking and alcohol consumption also play a role.
How can I lower my cholesterol naturally?
Adopting a heart-healthy diet (rich in fruits, vegetables, whole grains, and lean proteins), staying physically active, maintaining a healthy weight, and avoiding smoking can help improve cholesterol levels over time.
Do I need to fast before this test?
Yes, fasting for 8–12 hours before the test is usually recommended to get an accurate reading. Your provider will give specific instructions if this applies to you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy