Total Protein in Serum or Plasma
This test measures the total amount of protein in your blood, which includes albumin and globulin proteins essential for maintaining fluid balance, immune function, and tissue repair.
["Your blood protein levels help ensure proper health and function of your body’s systems."]
Key facts at a glance
- LOINC
- 50363-1
- Short code
- Cmn pigweed IgE/IgE total %
- Synonyms
- Cmn pigweed IgE/IgE total %
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order a total protein test to check for conditions affecting protein production, such as liver disease, kidney disease, malnutrition, or certain immune disorders. It can also help diagnose or monitor conditions like multiple myeloma, chronic inflammation, or dehydration.
What to Expect Before the Test
No special preparation is needed for this test. You may have a small needle inserted into a vein (usually in your arm) to draw blood. If you’re on blood thinners, let your healthcare provider know before the test.
What Happens During the Test
Blood is collected in a tube and sent to a lab for analysis. The test typically takes a few minutes, and you’ll feel minor discomfort from the needle insertion.
What the Results Mean
Results are compared to standard ranges, but individual results can vary based on age, health, and other factors. Low protein levels may indicate malnutrition or liver/kidney issues, while high levels could signal dehydration, inflammation, or overproduction of proteins.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal total protein levels can signal underlying health issues. For example, low protein may reflect poor nutrient absorption or organ dysfunction, while elevated levels could indicate conditions like multiple myeloma or severe dehydration. Always discuss results with your doctor for personalized interpretation.
Short name
Total Protein
Frequently asked questions
What causes low total protein levels?
What causes high total protein levels?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy