Cytomegalovirus Antibody, Total (Serum/Plasma) – Immunoassay
This test measures the presence of antibodies against cytomegalovirus (CMV), a common virus that can affect nearly everyone at some point in life. Antibodies indicate your immune system has recognized and fought off the virus.
["This test helps assess past or current infection by CMV, which can have implications for health, pregnancy, or immune function."]
Key facts at a glance
- LOINC
- 9513-3
- Short code
- CMV Ab Titr Ser CF
- Synonyms
- CMV Ab Titr Ser CF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- comp-fix
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects total antibodies (both IgG and IgM) produced by your immune system in response to CMV exposure. IgG antibodies typically develop after an initial infection or vaccination and can persist for years, while IgM antibodies appear earlier during an active infection.
Why Might You Need This Test?
Doctors may order this test if you have symptoms of CMV infection (e.g., fatigue, swollen lymph nodes, or organ-specific issues), if you’re immunocompromised (e.g., due to HIV, chemotherapy, or organ transplant), or if you’re pregnant and at risk of passing CMV to your baby.
Who Should Consider This Test?
People at higher risk of CMV complications, such as transplant recipients, those with weakened immune systems, or pregnant individuals, may be tested. It’s also used in screening for CMV in blood donors or to monitor chronic infections.
What to Expect Before the Test
No special preparation is needed. A blood sample is drawn from a vein in your arm. You may feel slight discomfort, but it usually lasts only a few minutes. If you’re pregnant or have a history of bleeding disorders, let your provider know before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results indicate past or current CMV infection. High IgM levels suggest an active infection, while IgG alone may reflect past exposure. In immunocompromised individuals, CMV can cause severe illness, including organ damage or infections in the lungs, brain, or eyes. Pregnant women with CMV should consult their doctor to assess risks to the fetus.
Short name
CMV Antibody Test
Frequently asked questions
How long does it take to get results?
What does a positive result mean for my health?
Can I get CMV from my partner or family?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy