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C-reactive protein (CRP) measured by high-performance liquid chromatography (HPLC) or similar quantitative method

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when your body is fighting inflammation or infection.

Quick summary

["High CRP levels may signal inflammation, often used to check for infections or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49349-4
Short code
CMV DNA # BAL NAA+probe
Synonyms
CMV DNA # BAL NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to monitor inflammation, check for infections (like pneumonia or sepsis), evaluate conditions like arthritis or heart disease, or assess response to treatment for inflammatory conditions.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein (usually in your arm) to draw blood. If you’re concerned about needles, let your healthcare provider know.

What the Results Mean

Results are not provided as a single numeric range. Instead, they’re compared to your doctor’s clinical judgment, patient history, and other test results. Elevated levels may indicate inflammation, while normal levels suggest no significant inflammation.

Common Conditions Monitored

This test helps diagnose or track conditions like infections, autoimmune diseases (e.g., rheumatoid arthritis), heart disease, or inflammatory bowel disease. It’s also used to check for early signs of illness in people with weakened immune systems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a marker of systemic inflammation. While it doesn’t pinpoint the cause of inflammation, it’s a useful tool for doctors to guide treatment and monitor disease activity. Always discuss results with your healthcare provider.

Short name

CRP (High Sensitivity)

Frequently asked questions

What causes CRP levels to be high?
High CRP levels can be caused by infections (like colds or flu), injuries, surgeries, or inflammatory diseases. Stress, certain medications, or even pregnancy can also affect CRP levels.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition and treatment plan. Regular monitoring may be needed if you have chronic inflammation or a history of infections.
Can I eat or drink before this test?
You can eat and drink normally before this test. No fasting is required for CRP testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy