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Cystatin C, Serum Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of cystatin C, a protein produced by all cells in your body. It helps assess your kidneys' function.

Quick summary

["Cystatin C is a simple blood test to check kidney health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100676-6
Short code
CMV DNA Bld NAA+probe-Log IU
Synonyms
CMV DNA Bld NAA+probe-Log IU
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate kidney function, especially if you have symptoms like fatigue, swelling, or changes in urine output. It’s also used to monitor kidney disease progression or response to treatment. Cystatin C is useful because it doesn’t depend on kidney filtration rates like other tests, making it more reliable in some cases.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your provider know before the test.

What Happens During the Test?

A healthcare professional will clean your arm and insert a needle to collect a small amount of blood. The blood will be sent to a lab for analysis.

What Are the Results?

Results are typically reported as a concentration value in milligrams per deciliter (mg/dL). Your provider will interpret the result in relation to your health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cystatin C is a sensitive marker for kidney function. Elevated levels may indicate reduced kidney function or kidney disease, even in people with normal blood pressure and no other symptoms. It can also help detect kidney problems early, especially in individuals with diabetes or high blood pressure. This test is often used alongside other measures, like creatinine, to get a fuller picture of kidney health.

Short name

Cystatin C

Frequently asked questions

Why might my doctor order this test?
Your doctor may order this test to check if your kidneys are working properly, especially if you have symptoms like swelling, frequent urination, or fatigue. It can also be used to monitor kidney disease, track how well treatments are working, or check for kidney problems in people with other health conditions like diabetes or high blood pressure.
How does cystatin C differ from creatinine?
Cystatin C is produced by all cells in your body and doesn’t depend on kidney function to be filtered out. This makes it a more consistent marker for kidney health compared to creatinine, which can be affected by muscle mass and hydration levels.
Can I eat or drink before this test?
No special diet or fasting is required for this test. You can eat and drink normally before your blood draw.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy