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Bronchial Lavage Fluid Alpha-1 Antitrypsin (A1AT) Content by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of Alpha-1 Antitrypsin (A1AT) in fluid collected from your airways, which may help assess lung health or inflammation.

Quick summary

["A1AT helps protect lung tissue; low levels may indicate lung disease or inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35401-9
Short code
CMV DNA Bronch Ql NAA+probe
Synonyms
CMV DNA Bronch Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like chronic cough, shortness of breath, or lung conditions such as chronic obstructive pulmonary disease (COPD), cystic fibrosis, or pulmonary fibrosis. It can also be used to monitor lung inflammation or response to treatment.

What to Expect Before the Test

You’ll likely undergo a bronchoscopy, where a thin tube is inserted through your nose or mouth into your airways. A small amount of fluid will be collected from your lungs using a specialized probe. You may feel mild discomfort, but it’s generally quick and done under sedation or local anesthesia.

What the Test Results Mean

A1AT levels in bronchial lavage fluid can help identify whether inflammation or lung damage is present. Abnormal results may suggest conditions like alpha-1 antitrypsin deficiency, infections, or other lung diseases. Your provider will interpret results in the context of your symptoms and medical history.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions like chronic lung diseases, lung infections, or inflammatory lung disorders. It may also help evaluate lung function in patients with genetic or acquired lung conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Alpha-1 antitrypsin (A1AT) is a protein that protects lung tissue from damage. Low levels in bronchial fluid may indicate underlying lung disease, including alpha-1 antitrypsin deficiency, which can lead to emphysema or chronic bronchitis. Monitoring A1AT levels helps guide treatment decisions and manage symptoms effectively.

Short name

A1AT in Bronchial Lavage Fluid

Frequently asked questions

What Does a Low or High Level Indicate?
Low levels of A1AT in bronchial fluid may suggest inflammation, lung damage, or genetic deficiency. High levels could indicate acute infection or other inflammatory processes, but interpretation depends on clinical context.
How Often Should This Test Be Done?
The frequency depends on your condition. If you have a chronic lung disease, your provider may recommend periodic testing to monitor progression or response to treatment. Follow-up schedules are tailored to your individual needs.
Is There Any Preparation Needed Before the Test?
No special preparation is typically required, but you may need to fast or avoid certain medications depending on the procedure. Always follow your healthcare provider’s instructions for the day of the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy