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Cytomegalovirus (CMV) DNA in Plasma/Serum (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of cytomegalovirus (CMV) genetic material in your blood or plasma. It helps determine if you have an active CMV infection.

Quick summary

["Active CMV infection may require treatment or monitoring."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88535-0
Short code
CMV DNA DBS Ql NAA+probe
Synonyms
CMV DNA DBS Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of infection, such as fever, fatigue, or organ-related issues, or if you’re immunocompromised (e.g., due to HIV, chemotherapy, or organ transplant). It can also be used to monitor treatment progress or detect early signs of infection in high-risk individuals.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample (plasma or serum) via a simple venipuncture. If testing urine or other fluids, follow your provider’s instructions for sample collection.

What the Test Results Mean

Positive results indicate the presence of CMV DNA, suggesting an active infection. Negative results mean no detectable genetic material was found. Results are qualitative (present/absent) unless specified otherwise.

Possible Treatments and Monitoring

If you test positive, your provider may recommend antiviral medications to manage symptoms or suppress the virus. Monitoring may include repeat testing to track response to treatment or disease progression.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CMV DNA Test

Frequently asked questions

What does a positive result mean for my health?
A positive result means your body is actively fighting CMV. This could indicate an infection that may need treatment, especially if you’re immunocompromised. Your provider will discuss next steps based on your symptoms and overall health.
Can I get CMV from this test?
No, this test does not expose you to CMV. It only detects the virus’s genetic material in your blood or plasma. Follow all lab instructions to prevent contamination.
How often will I need this test?
Your provider will determine the frequency based on your medical needs. Some patients need retests during treatment or if symptoms return, while others may only need it once for monitoring.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy