Cytomegalovirus (CMV) Antibody, IgM and IgG in Serum/Plasma (Screen and Confirm)

Why This Test Is Done

Doctors may order this test if you have symptoms like fever, fatigue, or organ issues that could be linked to CMV, especially if you have a weakened immune system (e.g., from HIV, chemotherapy, or organ transplant). It’s also used to monitor people at higher risk of infection, such as pregnant women or those with certain immune disorders.

How the Test Works

The test uses a blood sample to detect two types of antibodies: IgM (indicating recent or acute infection) and IgG (indicating past infection or ongoing immunity). The results help determine if you’ve been exposed to CMV and whether your body is actively fighting it.

Sample Collection and Preparation

A small blood sample is drawn from your arm. The blood is processed to separate serum or plasma, which is then tested for antibodies using immunoassay methods (like enzyme-linked immunosorbent assay, or ELISA).

What the Results Mean

Positive IgM results suggest a recent infection, while positive IgG results indicate past exposure. Combined results can show whether you’re currently infected, recovering, or immune. Always discuss results with your healthcare provider for personalized interpretation.