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Cytomegalovirus (CMV) DNA in Plasma/Serum (Quantitative Probe)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cytomegalovirus (CMV) genetic material in your blood. It helps track whether the virus is active or inactive in your body.

Quick summary

["This test helps monitor CMV infection, especially in people at higher risk of complications."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101947-0
Short code
CMV DNA Resp Ql NAA+probe
Synonyms
CMV DNA Resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have a weakened immune system (such as from HIV/AIDS, chemotherapy, or organ transplant), symptoms like fever, fatigue, or organ issues, or if you’ve been exposed to CMV. It’s also used to check how well treatments are working.

How the Test Works

A small blood sample is taken, and the genetic material (DNA) from CMV is detected using a specialized probe. The test measures how much CMV DNA is present, which can indicate active infection levels.

What the Results Mean

High levels of CMV DNA often mean the virus is actively replicating and may require treatment. Low or undetectable levels suggest the virus is likely inactive. Your provider will interpret results in the context of your symptoms and medical history.

Common Reasons for Testing

This test is particularly useful for people with weakened immune systems, pregnant women (to check for CMV in newborns), or those undergoing treatments that suppress the immune system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CMV DNA Load

Frequently asked questions

What does a positive result mean?
A positive result means your body is actively producing CMV DNA, which often signals an active infection. This may require medical evaluation to determine if treatment is needed.
How often will I need this test?
Your provider will decide how often you need retesting based on your medical condition, treatment plan, and symptoms. Follow-up tests may be scheduled if you’re undergoing treatment for CMV.
Can I eat or drink before the test?
You can eat and drink normally before the test, as it’s a blood draw and doesn’t require fasting. However, always follow your provider’s specific instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy