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Cystatin C Quantitative Measurement, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of cystatin C, a protein produced by all cells in your body that helps regulate cell growth. It’s often used to assess kidney function.

Quick summary

["Cystatin C helps monitor kidney health and may be used alongside other tests to check for kidney disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34720-3
Short code
CMV DNA Spec NAA+probe-aCnc
Synonyms
CMV DNA Spec NAA+probe-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to evaluate kidney function, especially if you have symptoms like fatigue, swelling, or changes in urine output. It can also be used to monitor kidney disease progression or guide treatment decisions, such as for patients on dialysis or with certain medications.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm, by a healthcare professional. You may feel a small pinch when the needle goes in, but the process is quick. The blood is then sent to a lab for testing.

What Should You Know Before Testing?

No special preparation is usually needed, but you may be asked to avoid certain medications or foods for a short time if instructed by your doctor. Drink plenty of water the day of the test to help your kidneys function normally.

What Are Common Results?

Results are typically reported as a concentration level of cystatin C in the blood. While reference ranges can vary by lab, higher levels may indicate reduced kidney function, while lower levels may suggest overproduction or other conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cystatin C is a more reliable marker than traditional blood tests like creatinine for assessing kidney function, especially in people with diabetes, older adults, or those with muscle disorders. It can help detect early kidney damage or monitor kidney disease over time, as it doesn’t depend on muscle mass or diet.

Short name

Cystatin C

Frequently asked questions

How long does it take to get my results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing times. Your doctor will contact you once they have the results, so check with them for an estimated timeline.
Do I need to fast before this test?
No fasting is required for this blood test. However, if your doctor has specific instructions, follow them to ensure accurate results.
Can diet or medications affect cystatin C levels?
Dietary factors like protein intake or hydration status can influence kidney function indirectly, but cystatin C itself is not strongly affected by diet. Some medications, such as those affecting kidney function, may also influence results, so discuss any medications with your doctor before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy