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C-reactive protein (CRP) with high-sensitivity immunoassay (hs-CRP)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when inflammation is present, often used to check for low-grade inflammation or infection.

Quick summary

["High-sensitivity CRP helps track subtle inflammation that may not show up with standard tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72605-9
Short code
CMV gp Gentyp Spec NAA+probe
Synonyms
CMV gp Gentyp Spec NAA+probe
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to monitor chronic conditions like heart disease, arthritis, or autoimmune disorders, or to assess risk for future health issues. It can also help evaluate inflammation after surgery, trauma, or infection.

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your doctor know before the test.

Results are not given in absolute numbers but compared to your doctor’s interpretation. Higher levels may indicate inflammation, while lower levels suggest reduced risk. Always discuss results with your healthcare provider.

This test is often used to monitor conditions like coronary artery disease, rheumatoid arthritis, or inflammatory bowel disease. It can also help screen for risk of future heart problems.

While CRP is a marker for inflammation, it doesn’t diagnose a specific condition. Your doctor will use it alongside other tests and symptoms to guide treatment.

Most people experience only mild discomfort or bruising at the injection site. Rarely, there may be a slight reaction like redness or swelling.

If you notice unusual pain, bleeding, or signs of infection (like fever) at the site, contact your doctor immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High-sensitivity CRP is a sensitive marker for systemic inflammation. Elevated levels can signal chronic inflammation, which may contribute to conditions like cardiovascular disease, diabetes, or certain cancers. It’s particularly useful for identifying patients at higher risk for complications, even if symptoms are mild.

Short name

High-sensitivity CRP

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your health needs. It may be done annually for risk assessment or more often if you have an ongoing condition requiring monitoring.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and smoking can influence CRP levels. Eating a heart-healthy diet, staying active, and avoiding smoking may help lower inflammation.
Is this test the same as a standard CRP test?
No, this is a high-sensitivity version that detects much smaller amounts of CRP, making it more precise for detecting low-level inflammation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy