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C-reactive protein (CRP) by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by the liver in response to inflammation, helping detect low-level inflammation in your body.

Quick summary

["CRP helps track subtle signs of inflammation that may not show up in other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11008-0
Short code
CMV IgG Titr CSF IF
Synonyms
CMV IgG Titr CSF IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82977
SNOMED
3110003
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why is this test done?

Your healthcare provider may order this test to monitor chronic conditions like heart disease, rheumatoid arthritis, or to check for early signs of infection or inflammation after surgery, injury, or illness.

What does a high or low result mean?

Elevated CRP levels often indicate inflammation, infection, or autoimmune conditions. Very low levels may suggest a lack of inflammation, though this isn’t always reliable on its own.

How is the test performed?

A blood sample is drawn from a vein in your arm. The sample is sent to a lab where it’s analyzed using nephelometry, a method that measures how particles scatter light to detect CRP levels.

What should you do before the test?

Avoid strenuous exercise or taking anti-inflammatory medications (like ibuprofen) 24 hours before the test, as they may affect results.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: csf

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (High-Sensitivity)

Frequently asked questions

Does CRP change with diet?
Diet can influence inflammation indirectly—eating a heart-healthy diet (rich in fruits, vegetables, and omega-3s) may help lower CRP over time, but results depend on overall health and other factors.
Can CRP be affected by stress?
Chronic stress can raise CRP levels, but acute stress may not have a strong immediate effect. Long-term stress management may help support healthier inflammation levels.
Is CRP the same as a standard CRP test?
Yes, this is a high-sensitivity CRP test, which detects smaller amounts of CRP than standard tests, making it more sensitive for detecting mild inflammation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy