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Serum or plasma concentration of vitamin K-dependent coagulation factors (qualitative or semi-quantitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain blood proteins that help your blood clot properly. It may be used to check for vitamin K deficiency or liver disease.

Quick summary

["Assesses blood clotting factors to identify potential issues with clotting or bleeding disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111270-5
Short code
CMV IgM Msmt SerPl
Synonyms
CMV IgM Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test evaluates the presence and activity of vitamin K-dependent coagulation factors, which play a key role in blood clotting. These factors include proteins like prothrombin, factors VII, IX, and X. The test may be qualitative (yes/no) or semi-quantitative, depending on the method used to detect them.

Why It’s Done

Your healthcare provider may recommend this test if you have symptoms of bleeding disorders, liver disease, or if you’re taking medications that affect blood clotting. It can also help monitor vitamin K levels or assess response to treatment.

Common Uses

This screening is often used as part of a broader evaluation for conditions like vitamin K deficiency, liver dysfunction, or inherited clotting disorders. It may also be performed in patients undergoing surgery or treatment for bleeding risks.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before drawing blood. Wear a loose shirt for easy access to your arm.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin K-dependent coagulation factor screening

Frequently asked questions

How long will results take to return?
Results are typically available within a few days to a week, depending on your lab. Follow-up with your healthcare provider to discuss next steps if needed.
Can I eat or drink before this test?
You may eat and drink normally unless instructed otherwise by your provider. Some tests require fasting, but this one does not.
What are the normal results?
There are no specific numeric ranges provided for this qualitative/semi-quantitative test. Results are interpreted based on whether factors are present or absent, often compared to your baseline or clinical symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy