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Serum or plasma concentration of vitamin K-dependent coagulation factors (qualitative or semi-quantitative screening/confirmation)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain proteins in your blood that help control blood clotting. It may be used to check for deficiencies or abnormalities in these proteins, which can affect how easily your blood clots or bleeds.

Quick summary

["Assesses blood clotting factors to identify potential bleeding or clotting disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5126-8
Short code
CMV IgM SerPl IA-aCnc
Synonyms
CMV IgM SerPl IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects levels of specific vitamin K-dependent coagulation factors, such as factors II (prothrombin), VII, IX, and X. These factors are essential for normal blood clotting. The method used may involve a qualitative or semi-quantitative approach, often through a blood clot formation test or similar assay, to screen for deficiencies or dysfunctions.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like excessive bleeding, easy bruising, prolonged bleeding from cuts, or if you’re taking medications that affect blood clotting. It can also be used to monitor conditions like liver disease, vitamin K deficiency, or certain blood disorders.

Common Reasons for Testing

This test is often performed during initial evaluations for bleeding disorders, after trauma or surgery, or in patients with known liver disease. It may also be part of routine monitoring for those on anticoagulant therapy.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma, which is then analyzed. The test may not require fasting, but follow your provider’s instructions for best results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin K-dependent coagulation factor screening

Frequently asked questions

How long will results take to return?
Results may take several days to a few weeks, depending on the laboratory’s processing time and whether confirmatory testing is needed. Your healthcare provider will discuss the results with you once available.
What does a low or high result mean?
Low levels of these coagulation factors may indicate bleeding disorders, liver disease, or vitamin K deficiency. High levels could suggest certain liver conditions or other rare metabolic issues. Your provider will interpret results in the context of your overall health and symptoms.
Can I eat or drink before this test?
No specific dietary restrictions are typically required for this test, but always follow your healthcare provider’s instructions. Avoid alcohol or medications that may affect blood clotting before the test if advised.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy