Cytomegalovirus (CMV) Antibody, IgM and IgG, Serum/Plasma

What Does This Test Measure?

The CMV antibody test checks for two types of antibodies—IgM and IgG—in your blood. IgM antibodies typically appear early after infection and can indicate a recent exposure. IgG antibodies usually develop later and suggest past infection or immunity. Together, these antibodies help track the timeline and severity of your CMV exposure.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms of infection (like fever, fatigue, or organ-related issues), if you’re immunocompromised (e.g., due to HIV, chemotherapy, or organ transplant), or if you’re a pregnant woman to check for CMV risk to your baby.

Who Should Consider This Test?

People at higher risk for complications from CMV, such as those with weakened immune systems, pregnant individuals, or those with chronic illnesses like kidney disease, may need this test to monitor or prevent spread of the virus.

What Does a Positive Result Mean?

A positive result for either IgM or IgG antibodies means you’ve likely been exposed to CMV. IgM alone suggests a recent infection, while IgG alone may indicate past exposure or immunity. A combination of both could mean you’ve had the virus and developed immunity over time.