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C-reactive protein (CRP) by nephelometry (high-sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when your body is fighting inflammation or infection.

Quick summary

["A high CRP level may signal inflammation needing further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43707-9
Short code
CMV Tiss Ql Shell Vial Cult
Synonyms
CMV Tiss Ql Shell Vial Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
shell-vial-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for signs of inflammation, monitor conditions like arthritis or heart disease, or assess response to treatment. High-sensitivity CRP is often used to detect early signs of inflammation that standard CRP might miss.

What Does the Result Mean?

Results are not provided with specific numeric ranges. Your doctor will interpret the result in the context of your health history and other tests. Elevated levels may indicate inflammation, infection, or autoimmune conditions.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is sent to a lab where it is analyzed using a nephelometry method to measure CRP levels precisely.

What Should You Expect Before the Test?

No special preparation is needed. You may eat and drink normally before the test. Let your doctor know about any medications or conditions that might affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

Your doctor may use this test to monitor chronic conditions like rheumatoid arthritis or cardiovascular disease, evaluate symptoms of infection or inflammation, or guide treatment decisions.
CRP levels can rise quickly in response to infections, injuries, or immune system activity. It’s not a direct marker of infection but often used alongside other tests.
How often should I get this test?
Frequency depends on your medical needs. Your doctor will determine how often to repeat the test based on your condition and response to treatment.
Can diet or exercise affect CRP levels?
While diet and exercise may influence inflammation, CRP levels are primarily a reflection of your body’s current inflammatory state. Your doctor will consider lifestyle factors when interpreting results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy