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Cytomegalovirus (CMV) Genomic Mutation Detection (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific genetic mutations associated with cytomegalovirus (CMV), a common virus that can affect the immune system.

Quick summary

["Assists in assessing risk for CMV-related infections or complications in patients with weakened immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106861-8
Short code
CMV UL56 gene Mut Det Islt
Synonyms
CMV UL56 gene Mut Det Islt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects changes in the genetic material of CMV. These mutations can indicate a higher likelihood of infection or altered viral behavior, which may be important for certain patient groups, such as those with HIV/AIDS, organ transplant recipients, or those undergoing chemotherapy.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have a higher risk of CMV infection, such as after an organ transplant, if you have a weakened immune system, or if you’re being evaluated for conditions linked to CMV exposure.

Sample Collection and Preparation

A blood sample (serum or plasma) is collected during a routine venipuncture. The sample is processed to extract genetic material for analysis.

What to Expect Before the Test

No special preparation is needed, but inform your provider if you’re taking medications that could affect blood tests or if you have a history of bleeding disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CMV Gene Mutation Test

Frequently asked questions

Why might this test be important for my health?
This test helps identify genetic markers that may influence how CMV behaves in your body. For patients with compromised immune systems, detecting these mutations can guide treatment decisions, such as adjusting antiviral therapy or monitoring for infection.
What does a positive result mean?
A positive result indicates the presence of CMV genetic mutations, which may suggest an increased risk of infection or altered viral activity. Your provider will interpret results in the context of your medical history and symptoms.
How often should I get this test?
The frequency depends on your medical condition and risk factors. Your healthcare provider will determine the best timing based on your care plan.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy