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Cytomegalovirus (CMV) Genomic Mutation Detection by Sequencing

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific genetic mutations in your body’s cells that may be linked to cytomegalovirus (CMV) infection. It helps determine if you have a genetic predisposition to CMV-related health issues.

Quick summary

["This test may help guide treatment or monitoring for CMV infection risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72833-7
Short code
CMV UL97 gene Mut Det Islt
Synonyms
CMV UL97 gene Mut Det Islt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a weakened immune system (e.g., due to HIV/AIDS, chemotherapy, or organ transplant), are pregnant and at higher risk of CMV transmission, or have a history of CMV infection. It may also be used in research or specialized clinical settings to assess genetic susceptibility.

How the Test Works

A small blood sample is collected to analyze your DNA. Advanced laboratory techniques, such as sequencing, identify any mutations in the CMV-related genes. These mutations can indicate whether you carry certain genetic variations that may affect how your body responds to CMV.

Sample Collection and Preparation

You will have a simple blood draw, usually taken from your arm. The blood sample is then sent to a lab for genetic analysis. No special preparation is needed, but fasting may not be required unless instructed by your provider.

What to Expect After the Test

Results are typically reported as positive or negative for specific mutations. Your healthcare provider will discuss the findings with you, explaining their potential implications based on your medical history and overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CMV Mutation Screening

Frequently asked questions

What does this test measure?
This test detects genetic mutations in cells that may be associated with cytomegalovirus (CMV) infection. While mutations alone don’t confirm infection, they can help identify individuals at higher risk of complications if infected. Results may influence decisions about preventive measures, monitoring, or treatment strategies.
How might my results affect my care?
If mutations are found, your provider may recommend closer monitoring, tailored preventive strategies, or adjustments to immune-suppressing medications. If no mutations are detected, it does not rule out CMV infection entirely, as other factors may play a role.
Can this test be used for routine screening?
No, this test is not typically used for general screening. It is usually reserved for specific clinical situations, such as high-risk patients, research studies, or specialized diagnostic purposes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy