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Bilirubin, Total (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Bilirubin helps diagnose liver disease, bile duct blockages, or hemolytic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40871-6
Short code
CNBP Mut Anl Bld/T
Synonyms
CNBP Mut Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Your doctor may order this test if you have symptoms like jaundice (yellowing of skin/eyes), unexplained fatigue, or signs of liver problems. It can also help monitor conditions like hemolytic anemia or bile duct issues.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. It usually takes a few minutes, and you may feel a brief pinch.

Common Causes of Abnormal Results

High bilirubin levels may indicate liver disease, bile duct blockage, or red blood cell breakdown. Low levels are less common but could suggest liver dysfunction or certain medications.

What the Results Mean

Results are compared to a general reference range, but exact values depend on your health. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Serum Bilirubin

Frequently asked questions

Will this test affect my medications?
Some medications (e.g., certain antibiotics, antifungals) can affect bilirubin levels. Always inform your doctor about all medications, including supplements.
How often should I get this test?
Frequency depends on your health. Doctors may order it periodically for chronic liver conditions or during follow-ups for suspected jaundice.
Can I eat or drink before the test?
You can eat normally, but avoid heavy meals right before drawing blood. Hydration is fine unless your doctor specifies otherwise.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy