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Arterial Blood Carbon Dioxide Partial Pressure (Calculated)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of carbon dioxide gas dissolved in your blood from an artery (arterial blood), using a calculated value based on blood chemistry measurements. It helps assess how well your body is balancing oxygen and carbon dioxide levels.

Quick summary

["This test helps doctors diagnose and monitor conditions affecting gas exchange in your lungs and blood circulation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34728-6
Short code
CO2 Bld Calc-sCnc
Synonyms
CO2 Bld Calc-sCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
22
Ref high
28
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
calculated
CPT
82374
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like shortness of breath, chest pain, or fatigue that could indicate problems with how your lungs or heart move oxygen and carbon dioxide. It’s also used in critical care settings, such as the ICU, to monitor patients with severe respiratory or circulatory issues.

What Does the Result Mean?

The result is expressed in millimeters of mercury (mmHg) and is calculated from other blood measurements. Abnormal values may suggest conditions like respiratory failure, metabolic issues, or fluid imbalances.

How Is the Test Performed?

A small sample of blood is taken from an artery in your arm or wrist. The blood is analyzed in a lab to determine the carbon dioxide levels, and the result is calculated based on standard formulas.

What Are Common Causes of Abnormal Results?

Low arterial CO₂ levels (hypocapnia) may occur due to hyperventilation, lung diseases, or overbreathing. High levels (hypercapnia) can result from conditions like chronic obstructive pulmonary disease (COPD), obesity hypoventilation syndrome, or kidney problems.

Reference range

Adult: 22-28 mmol/LN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a key role in diagnosing and managing respiratory and metabolic disorders. It helps doctors adjust treatments, such as oxygen therapy or mechanical ventilation, to improve oxygenation and carbon dioxide removal in the body.

Short name

CO₂ (Arterial) Calculation

Frequently asked questions

What does an abnormal arterial CO₂ level indicate?
An abnormal result may signal underlying health issues like lung disease, heart problems, or metabolic imbalances. Your doctor will review your symptoms and other test results to determine the cause.
How often should I expect this test?
The frequency depends on your medical condition. Some patients need this test regularly, especially if they have chronic lung or heart disease, while others may only need it during acute care or monitoring.
Can I prepare for this test?
No special preparation is needed, but inform your doctor about any medications or conditions that might affect blood results, such as recent illness or dehydration.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy