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Carbon Dioxide in Blood (Total, Venous)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of carbon dioxide dissolved in your blood drawn from a vein. It helps assess how well your body is balancing acidity and alkalinity (pH) and how efficiently your lungs are removing waste gases.

Quick summary

["A key check for acid-base balance and lung function in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39465-0
Short code
CO2 BldCoV-sCnc
Synonyms
CO2 BldCoV-sCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
22
Ref high
28
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82374
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Your body naturally regulates acidity and alkalinity through chemical processes, including carbon dioxide. When levels are too high or too low, it can lead to conditions like respiratory acidosis or alkalosis. This test helps doctors identify imbalances that may require medical attention, such as breathing disorders or kidney issues.

When You Might Need It

Doctors may order this test if you have symptoms like shortness of breath, chest pain, confusion, or rapid breathing. It’s also used in monitoring patients with chronic lung diseases, kidney problems, or metabolic disorders. Some people get it as part of routine blood work or during emergency evaluations.

What to Expect Before the Test

You’ll likely have a small needle inserted into a vein in your arm or hand to draw blood. It’s quick but may cause a brief pinch. Avoid eating or drinking for a short time before if instructed, as some labs check blood after fasting. Wear comfortable clothing if you need an arm raised.

What the Results Mean

Results are usually reported alongside your blood pH and oxygen levels. High carbon dioxide levels (hypercapnia) may indicate poor lung function or breathing issues, while low levels (hypocapnia) could suggest overbreathing or other metabolic factors. Your doctor will interpret results in the context of your symptoms and overall health.

Reference range

Adult: 22-28 mmol/LN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total CO₂ in Venous Blood

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 2 business days, depending on your lab’s processing time. Some urgent cases may get results sooner, especially if drawn at a hospital lab.
Can I eat or drink before this test?
Check with your doctor or lab technician about fasting requirements. Some tests are done on fasting blood, while others may be taken after eating. Follow their specific instructions to ensure accurate results.
What do I do if I feel dizzy or lightheaded during the blood draw?
Rest comfortably and stay hydrated afterward. If you experience severe pain, fainting, or unusual symptoms, contact your doctor immediately. They may adjust your care plan if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy