Carbon Dioxide in Blood (Total, Venous)
This test measures the amount of carbon dioxide dissolved in your blood drawn from a vein. It helps assess how well your body is balancing acidity and alkalinity (pH) and how efficiently your lungs are removing waste gases.
["A key check for acid-base balance and lung function in your blood."]
Key facts at a glance
- LOINC
- 39465-0
- Short code
- CO2 BldCoV-sCnc
- Synonyms
- CO2 BldCoV-sCnc
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 22
- Ref high
- 28
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82374
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Your body naturally regulates acidity and alkalinity through chemical processes, including carbon dioxide. When levels are too high or too low, it can lead to conditions like respiratory acidosis or alkalosis. This test helps doctors identify imbalances that may require medical attention, such as breathing disorders or kidney issues.
When You Might Need It
Doctors may order this test if you have symptoms like shortness of breath, chest pain, confusion, or rapid breathing. It’s also used in monitoring patients with chronic lung diseases, kidney problems, or metabolic disorders. Some people get it as part of routine blood work or during emergency evaluations.
What to Expect Before the Test
You’ll likely have a small needle inserted into a vein in your arm or hand to draw blood. It’s quick but may cause a brief pinch. Avoid eating or drinking for a short time before if instructed, as some labs check blood after fasting. Wear comfortable clothing if you need an arm raised.
What the Results Mean
Results are usually reported alongside your blood pH and oxygen levels. High carbon dioxide levels (hypercapnia) may indicate poor lung function or breathing issues, while low levels (hypocapnia) could suggest overbreathing or other metabolic factors. Your doctor will interpret results in the context of your symptoms and overall health.
Reference range
Adult: 22-28 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Total CO₂ in Venous Blood
Frequently asked questions
How long does it take to get results?
Can I eat or drink before this test?
What do I do if I feel dizzy or lightheaded during the blood draw?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy