Carbon Dioxide (Total) in Blood Gas Analysis
This test measures the total amount of carbon dioxide in your blood, which helps assess how well your body is balancing acidity and alkalinity (acid-base balance).
["Your blood’s CO₂ levels help doctors check for conditions like respiratory issues or metabolic disorders."]
Key facts at a glance
- LOINC
- 60789-5
- Short code
- CO2 gas del dur case Vol Gas DS
- Synonyms
- CO2 gas del dur case Vol Gas DS
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 22
- Ref high
- 28
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82374
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Total carbon dioxide (CO₂) in your blood includes both dissolved CO₂ and bicarbonate (HCO₃⁻), which are key components of your body’s acid-base balance. This test helps evaluate how efficiently your lungs remove CO₂ and how your kidneys adjust bicarbonate levels to maintain normal pH.
Why Might You Need This Test?
Doctors may order this test if you have symptoms like shortness of breath, chest pain, or fatigue, which could indicate problems with your lungs or kidneys. It’s also used during monitoring for conditions like heart failure, kidney disease, or severe infections.
Sample Collection and Preparation
This test requires a blood sample drawn from a vein, usually in your arm. The blood is analyzed immediately or sent to a lab to measure total CO₂ levels, often as part of a broader blood gas panel that also checks oxygen and pH levels.
What Are Common Results and Interpretation?
Results are typically reported alongside blood pH and oxygen levels to determine whether your acid-base balance is normal or if adjustments are needed. Elevated CO₂ levels may suggest respiratory issues, while low levels could indicate metabolic problems or overbreathing.
Reference range
Adult: 22-28 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Total CO₂ (Blood Gas)
Frequently asked questions
How often will I need this test?
What do my results mean if they’re outside of normal ranges?
Can I prepare for this test in any special way?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy