Carbon Dioxide Production Rate (Respiratory Metabolism)
This test measures how quickly your body produces carbon dioxide during respiration, often assessed in specialized metabolic studies to evaluate lung function and metabolic processes.
["Helps diagnose conditions affecting breathing or metabolism."]
Key facts at a glance
- LOINC
- 76265-8
- Short code
- CO2 production/BSA Respiratory
- Synonyms
- CO2 production/BSA Respiratory
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 22
- Ref high
- 28
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82374
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
This test evaluates the rate at which carbon dioxide is generated in your body during respiration. It is typically conducted in a controlled setting, such as a metabolic chamber, where you breathe normally while the machine measures the CO₂ expelled over time. This can help assess how efficiently your lungs and metabolic processes function together.
Why It Might Be Ordered
Your healthcare provider may order this test if you have symptoms like shortness of breath, fatigue, or if they suspect conditions like chronic obstructive pulmonary disease (COPD), lung infections, or metabolic disorders. It can also be used to monitor treatment effectiveness or before certain surgeries.
Preparation and Procedure
No special preparation is needed for this test. You will be placed in a sealed chamber where you breathe normally for a set period. The machine continuously measures the CO₂ concentration in your exhaled air. The test usually takes about 30 to 60 minutes and is painless.
What the Results Mean
Results are expressed as a rate of CO₂ production, often measured in milliliters per minute. While specific reference ranges can vary by lab, lower than expected rates may suggest lung or metabolic issues, while higher rates could indicate conditions like hyperventilation or certain metabolic disorders.
Reference range
Adult: 22-28 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CO₂ Production Rate
Frequently asked questions
What does a carbon dioxide production rate test involve?
How is this test different from a standard blood gas test?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy