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Staphylococcus aureus DNA detection by nucleic acid probe (qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Staphylococcus aureus* bacteria in your blood sample. It helps identify infections caused by this type of bacteria.

Quick summary

["This test quickly determines if *Staphylococcus aureus* is likely causing an infection in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70016-1
Short code
Coag neg Staph DNA Bld Ql NAA+probe
Synonyms
Coag neg Staph DNA Bld Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, chills, or signs of infection (such as redness, warmth, or swelling) that could be due to *Staphylococcus aureus*. It’s also used in certain hospital settings to detect infections in patients who are at higher risk, such as those with weakened immune systems or recent surgeries.

How the Test Works

The test uses a specialized probe to detect genetic material (DNA) from *Staphylococcus aureus*. If the bacteria are present, the probe binds to their DNA, confirming the infection. This method is highly sensitive and specific for this particular bacteria.

Sample Collection and Preparation

A blood sample is taken from you, usually from a vein in your arm. The blood is then processed to extract DNA for testing. This test does not require fasting or special preparation.

What to Expect After the Test

Results are typically available within 24 hours. If the test is positive, it means *Staphylococcus aureus* DNA was found in your blood, indicating an active infection. Your provider will discuss next steps, such as starting appropriate antibiotics.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Staph aureus DNA probe test

Frequently asked questions

What does a positive result mean?
A positive result strongly suggests an infection caused by *Staphylococcus aureus*. This bacteria can cause serious infections, including bloodstream infections, pneumonia, or skin/soft tissue infections. Early treatment with antibiotics is crucial to manage the infection effectively.
What does a negative result mean?
A negative result means no detectable *Staphylococcus aureus* DNA was found in the sample. However, it’s possible the infection is caused by a different bacteria or that the bacteria were not present at the time of testing. Follow-up testing or additional evaluation may be recommended if symptoms persist.
Can this test be used for other infections?
No, this test is specific for *Staphylococcus aureus* DNA. It cannot detect infections caused by other bacteria or viruses. If you have symptoms of infection, your provider may recommend other tests to rule out other causes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy