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Prothrombin Time (PT) with International Normalized Ratio (INR) – Plasma-Based

Published: August 9, 2026Updated: August 16, 2026

This test measures how long it takes for blood to clot, using plasma from your sample. It helps assess the function of blood clotting factors, often used to monitor treatments like warfarin.

Quick summary

["PT/INR checks your blood’s ability to clot safely and guides treatment for conditions affecting clotting."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6302-4
Short code
Coagulation normal/actual PPP PT
Synonyms
Coagulation normal/actual PPP PT
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
44
Ref high
147
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag-tissue-factor-induced
CPT
84075
SNOMED
27550007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is PT/INR Testing Used For?

PT/INR tests are primarily used to evaluate the effectiveness of anticoagulant medications (like warfarin) and to diagnose or monitor bleeding disorders. It also helps detect liver disease, since the liver produces many clotting factors.

How Is the Test Performed?

A blood sample is drawn, and plasma is separated. The test measures the time it takes for the plasma to clot under controlled conditions. The INR standardizes results across different labs by comparing your PT to a normal value.

What Does a PT/INR Result Mean?

Results are reported as a PT (time in seconds) and INR (a ratio). Higher INR values (above 1.0) may indicate too much clotting risk, while lower values (below 1.0) may suggest insufficient clotting. Your doctor will interpret results based on your medical condition and treatment needs.

Common Reasons for Testing

You might have a PT/INR test if you’re on blood thinners, have liver disease, experience frequent bruising or bleeding, or are at risk for clots. It’s also used before surgeries or procedures that could affect clotting.

Reference range

Adult: 44-147 U/LN/A

Specimen: plasma

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

PT/INR

Frequently asked questions

Why might my doctor order a PT/INR test?
Your doctor may recommend it to check if your blood thinner medication is working properly, to monitor a bleeding disorder, or to assess liver health. It’s also used before certain surgeries or procedures.
What can affect my PT/INR results?
Factors like diet (especially vitamin K-rich foods), certain medications (other than anticoagulants), liver disease, or infections can influence results. Always discuss your full medical history with your provider.
Do I need to prepare for this test?
No special preparation is needed, but avoid taking vitamin K supplements or certain medications (like NSAIDs) 2–3 days before testing. Follow your doctor’s instructions for any dietary restrictions related to anticoagulants.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy