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Coarse Granular Casts, Urine — Microscopic Semi-quantitative Count per High-Power Field

Published: August 9, 2026Updated: August 17, 2026

A urine microscopy test that measures coarse granular casts, which are structures formed in the kidney's microscopic tubules.

Quick summary

["Coarse granular casts in urine are a nonspecific finding that may occur with kidney stress or kidney disease and should be interpreted with other results."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
33226-2
Short code
Coarse Gran Casts #/area UrnS HPF
Synonyms
Coarse Gran Casts #/area UrnS HPF
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
10
Ref high
40
Critical range
0.5 N/A – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light-hpf
CPT
84484
SNOMED
302774002
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test examines a urine sample under a microscope to detect and estimate the number of coarse granular casts. These casts are small structures made of material and cellular debris that form inside the kidney's filtering tubules.

Why might I need this test?

Urine microscopy may be ordered during a routine urinalysis or to evaluate symptoms such as swelling, changes in urination, foamy urine, or suspected kidney problems. The result is one part of an overall assessment of kidney and urinary tract health.

How is the test performed?

A urine specimen is examined by microscopy, and coarse granular casts are reported as a semi-quantitative count, generally in relation to microscopic high-power fields. The sample is usually collected as a clean-catch, midstream urine specimen.

How do I prepare for the test?

Follow the laboratory's collection instructions, which may include cleaning the genital area and collecting a midstream sample in a sterile container. Tell your clinician if you have recently taken antibiotics, had a urinary infection, or are menstruating, as these factors can affect urine findings.

Reference range

Adult: 10-40 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Coarse Granular Casts

Frequently asked questions

Are coarse granular casts always a sign of kidney disease?
No. They can occur with temporary dehydration or increased kidney workload, but persistent or larger numbers may prompt evaluation for kidney disease. The result must be considered with symptoms and other laboratory findings.
What does a high-power field mean?
A high-power field is the area seen through the microscope at a particular magnification. Reporting casts in this way provides a semi-quantitative estimate of how many were seen in the urine sample.
Can this test be performed at home?
It is generally performed by a laboratory using a collected urine specimen. At-home urine dipsticks do not usually identify or count granular casts, so microscopy is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy