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Cobalt, Whole Blood — Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

Measures the amount of cobalt in a whole-blood sample to help evaluate exposure or cobalt released from a medical implant.

Quick summary

["This test measures cobalt in blood and may help identify excessive exposure or wear of certain metal implants."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
5625-9
Short code
Cobalt Bld-mCnc
Synonyms
Cobalt Bld-mCnc
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302773008
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

A cobalt whole-blood test measures the concentration of the element cobalt in your blood. It may be used to assess recent or ongoing exposure to cobalt or to investigate possible cobalt release from certain joint implants.

Why might I need this test?

Your doctor may order this test if you work with cobalt-containing materials, take a cobalt supplement, or have a metal implant that could release small amounts of metal. It may also be used when symptoms raise concern that a medical device is affecting your health.

How is the test performed?

A blood sample is collected, usually by venipuncture, and sent to a laboratory for specialized measurement. The laboratory reports the cobalt concentration in the sample, and your doctor interprets it along with your exposure history, symptoms, medications, and any implants.

How do I prepare for the test?

Follow your doctor's instructions about supplements and occupational exposure before the blood draw. Tell the laboratory and your doctor about any cobalt-containing supplements, recent work exposure, and medical implants, because these factors can affect the result.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: whole-blood

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher-than-expected cobalt level may indicate environmental or occupational exposure, intake of a cobalt supplement, or release of cobalt from a metal implant. The level should be interpreted with the timing of the blood draw and the patient's clinical context. An isolated result does not by itself establish toxicity or implant failure.

Short name

Cobalt, Whole Blood

Frequently asked questions

Does a high cobalt level mean I have cobalt poisoning?
Not necessarily. Elevated levels can reflect recent exposure, supplement use, or release from an implant, so your doctor must interpret the result alongside your history and symptoms.
Why is the sample called whole blood?
Whole blood includes red blood cells, white blood cells, and plasma. The test measures cobalt in that complete blood sample rather than only in the liquid portion.
Should I stop taking a cobalt supplement before the test?
Do not stop any supplement without medical advice. Tell your doctor and the laboratory when you last took it so the result can be interpreted correctly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy