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Cobalt and Creatinine, 24-Hour Urine

Published: August 9, 2026Updated: August 17, 2026

Measures cobalt in urine collected for 24 hours, with creatinine measured to help account for differences in urine concentration.

Quick summary

["This test can help assess recent cobalt exposure, while the creatinine result helps interpret the urine cobalt measurement."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
29934-7
Short code
Cobalt/Creat 24h Ur
Synonyms
Cobalt/Creat 24h Ur
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302773008
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of cobalt in urine collected over 24 hours. Creatinine is also measured to help adjust for how concentrated or dilute the urine is.

Why might I need this test?

It may be ordered to assess exposure to cobalt from workplace materials, contaminated products, certain supplements, or other sources. Your healthcare professional will interpret the result using your exposure history and symptoms.

How is the test performed?

You collect all urine into a labeled container for exactly 24 hours. The laboratory then measures cobalt and creatinine in the collected sample.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional, including the start and end times. Tell the laboratory about supplements, occupational exposure, or other possible cobalt sources, and do not change your diet or medications unless instructed.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Cobalt and Creatinine

Frequently asked questions

What does the 24-hour urine test show?
It shows how much cobalt was eliminated in the urine over one full day. The creatinine measurement helps account for differences in urine concentration.
Why was my urine collected for 24 hours?
A 24-hour collection provides a more complete picture of urinary cobalt than a single urine sample. It can also reduce the effect of urine concentration or dilution.
What can cause elevated urine cobalt?
Possible causes include occupational exposure, cobalt-containing supplements, contaminated food or products, and certain medical treatments. Discuss any potential exposure with your healthcare professional.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy