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Cobalt, 24-Hour Urine — Estimated Intake

Published: August 9, 2026Updated: August 17, 2026

Measures cobalt collected in urine over 24 hours to help estimate recent cobalt exposure from diet, supplements, medications, or occupational sources.

Quick summary

["This test estimates recent cobalt exposure by measuring how much cobalt your body excretes in urine over 24 hours."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
81127-3
Short code
Cobalt intake 24h Est
Synonyms
Cobalt intake 24h Est
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
estimated
CPT
84484
SNOMED
302773008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of cobalt excreted in urine over a 24-hour period. The result may be used to estimate recent cobalt intake or exposure, including exposure related to diet, supplements, medicines, or workplace contact.

Why might I need this test?

A clinician may order this test if you have recently been exposed to cobalt, work with cobalt-containing materials, or take a supplement that may contain cobalt. It can also help assess whether an unexplained exposure is contributing to symptoms.

How is the test performed?

You collect all urine produced during a full 24-hour period in a specially provided container. The laboratory measures the total cobalt in the collected sample and may use it to estimate your cobalt intake.

How do I prepare for the test?

Follow your clinician's instructions about cobalt-rich foods, supplements, and medicines. Keep collecting urine for the complete 24 hours, and note the date and time the collection began. If the collection is incomplete or the timing is wrong, the result may be unreliable.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher result may indicate that you have recently absorbed more cobalt than expected from food, supplements, medication, or environmental exposure. A lower result generally reflects less recent cobalt exposure. Urinary cobalt shows recent exposure rather than the total amount stored in the body, so results should be interpreted with your exposure history and symptoms.

Short name

24-Hour Urine Cobalt

Frequently asked questions

Does a 24-hour urine test show how much cobalt is in my body?
No. It estimates recent exposure by measuring cobalt eliminated in the urine. It does not directly measure the amount of cobalt stored in tissues or organs.
What can raise my urinary cobalt level?
Cobalt-containing supplements, certain medicines or nutritional products, some foods, and workplace exposure can all increase the result. Tell your clinician about any of these possibilities.
What if I miss part of the 24-hour urine collection?
An incomplete collection can make the result inaccurate or may require repeating the test. Contact the laboratory or your clinician for instructions if you miss a collection period or spill part of the sample.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy