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Cobalt, 24-Hour Urine, Quantitative

Published: August 9, 2026Updated: August 17, 2026

Measures cobalt in urine collected over 24 hours to help evaluate recent exposure to cobalt from occupational sources, supplements, or other sources.

Quick summary

["This test can help identify elevated cobalt exposure, but results should be interpreted with your exposure history and medical context."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
81126-5
Short code
Cobalt intake 24h Measured
Synonyms
Cobalt intake 24h Measured
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
measured
CPT
84484
SNOMED
302773008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of cobalt eliminated in your urine during a 24-hour collection. It is used mainly to assess recent exposure to cobalt.

Why might I need this test?

Your clinician may order it if you work with cobalt-containing materials, take cobalt supplements, have a possible exposure, or have symptoms that could be related to toxic exposure.

How is the test performed?

You collect all urine into a special container for exactly 24 hours. The laboratory measures the total cobalt amount and accounts for the collection volume and time.

How do I prepare for the test?

Follow your clinician's instructions about supplements, medications, and any possible cobalt exposure before collection. Record relevant occupational or environmental exposures and be sure to complete the full 24-hour collection.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated result may indicate recent exposure to cobalt, such as from industrial work, certain supplements, medical devices, or other sources. Urine cobalt generally reflects recent exposure and may be affected by the timing and completeness of collection. Your clinician will interpret the result using your history, symptoms, and other tests rather than a single value alone.

Short name

24-Hour Urine Cobalt

Frequently asked questions

What does a urine cobalt test measure?
It measures the amount of cobalt in a urine sample. A 24-hour collection provides information about your total cobalt excretion over that period.
What can cause high urine cobalt levels?
Possible causes include workplace exposure, cobalt-containing supplements, exposure to contaminated materials, or exposure associated with certain medical devices. The result should be interpreted alongside your exposure history.
Does this test show long-term cobalt exposure?
Urine testing most closely reflects recent exposure. Other tests or clinical information may be needed if the clinician is evaluating long-term or delayed effects.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy