Skip to content

Cobalt, Red Blood Cells — Substance Concentration

Published: August 9, 2026Updated: August 17, 2026

A test that measures the amount of cobalt in red blood cells to help assess exposure or possible cobalt-related effects.

Quick summary

["This test measures cobalt stored in red blood cells, which may help evaluate exposure to cobalt."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
50847-3
Short code
Cobalt RBC-sCnc
Synonyms
Cobalt RBC-sCnc
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
7
Ref high
56
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302773008
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of cobalt in red blood cells. Cobalt is a trace element found in the body and in some foods, supplements, industrial products, and medical devices.

Why might I need this test?

The test may be ordered to assess recent or ongoing cobalt exposure, particularly in someone who works with metals, batteries, welding materials, or cobalt-containing medical devices. It may also be used during the evaluation of unexplained symptoms or suspected metal exposure.

How is the test performed?

A blood sample is collected, and the laboratory separates red blood cells to measure their cobalt content. The result may be reported as a substance concentration, meaning the amount of cobalt per specified amount of red blood cell material.

How do I prepare for the test?

Follow the laboratory's instructions about timing and any supplements or occupational exposure to disclose. Do not stop prescribed medicines or supplements without medical advice, because supplements and workplace exposures can affect the result.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Red blood cell cobalt

Frequently asked questions

Is this the same as a serum cobalt test?
No. This test measures cobalt in red blood cells, while a serum cobalt test measures it in the liquid portion of blood. The two tests can provide different information and are not direct substitutes.
What can raise my red blood cell cobalt level?
Occupational exposure, certain supplements or products containing cobalt, and exposure related to some medical devices may raise the level. Recent exposure can also influence the result.
Does an abnormal result confirm cobalt poisoning?
No. An abnormal result suggests possible excess exposure or another cause of elevation but does not confirm poisoning by itself. Your clinician will interpret it with your medical history, symptoms, and other tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy