Skip to content

Cocaine Ethylene Glycol Metabolite Screening (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of cocaine metabolites in your blood, which can help determine if you’ve recently used cocaine.

Quick summary

["Detects recent cocaine use through its breakdown products in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110256-5
Short code
Cocaethylene Msmt SerPl
Synonyms
Cocaethylene Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’ve been exposed to cocaine, are suspected of misuse, or are undergoing treatment for substance use. It can also be part of a broader evaluation for overdose or poisoning.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein for blood collection. If you’re nervous, let your provider know—they can help make it more comfortable.

What the Test Results Mean

Positive results indicate recent cocaine use, but they don’t confirm the exact amount or timing. High levels may suggest recent exposure, while lower levels could mean earlier use or dilution in your system.

Common Causes of Abnormal Results

Abnormal results are most likely due to recent cocaine use. Other factors, like certain medications or medical conditions, could also affect metabolite levels, but this test focuses specifically on cocaine exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cocaine Metabolite Test

Frequently asked questions

How soon after use can this test detect cocaine?
Cocaine metabolites can appear in your blood within minutes to hours after use, but levels may peak and decline over several hours to days. Exact timing depends on how much was used and individual metabolism.
Can this test detect cocaine use from days or weeks ago?
No, this test primarily detects recent use (typically within hours to a few days). For longer-term use, urine or hair analysis may be more appropriate.
Does this test require fasting?
No fasting is required for this blood test. However, always follow your provider’s instructions for any other tests you may have scheduled.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy