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Ethanol and Cocaethylene Mass Concentration in Urine (24-hour collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of alcohol (ethanol) and a related substance (cocaethylene) in your urine over a 24-hour period. It helps assess alcohol exposure and potential mixing of alcohol with other substances.

Quick summary

["This test helps track alcohol use and possible drug interactions that may affect your health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
19408-4
Short code
Cocaethylene Ur-mCnc
Synonyms
Cocaethylene Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have concerns about heavy alcohol use, suspected drug-alcohol interactions, or if you’re part of a monitoring program (e.g., for substance use treatment). It can also be used in cases where alcohol levels in blood or breath tests are unclear or inconsistent with symptoms.

What to Expect Before the Test

You’ll collect a 24-hour urine sample starting from midnight one day and ending midnight the next. Follow your provider’s instructions carefully to ensure accurate results. Avoid certain medications or substances that could interfere with the test.

What the Results Mean

Results show the combined amount of ethanol and cocaethylene in your urine. High levels may indicate heavy alcohol use, possible mixing with cocaine or other stimulants, or other health risks. Your provider will interpret results in the context of your medical history and symptoms.

Common Causes of Abnormal Results

Elevated levels may be due to heavy alcohol consumption, mixing alcohol with cocaine or other stimulants, or certain medical conditions. False positives can occur if you’ve consumed certain medications or foods. Always discuss results with your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is particularly useful for detecting alcohol exposure in cases where blood or breath tests are unreliable (e.g., in chronic alcohol users, overdose scenarios, or postmortem evaluations). Cocaethylene, a metabolite formed when alcohol and cocaine interact, can indicate dangerous mixing and may require immediate medical attention.

Short name

24-Hour Urine Ethanol & Cocaethylene Mass

Frequently asked questions

How long does it take to get my results?
Results are typically processed within 1–3 business days after the urine sample is submitted. Your healthcare provider will contact you directly with the final report.
Can I drink alcohol before this test?
No, avoid alcohol for at least 24 hours before starting your urine collection to ensure accurate results. If you’re unsure, ask your provider for specific guidelines.
What if I miss a day of urine collection?
If you miss any part of the 24-hour collection, you’ll need to restart the process. Missing even a small amount may affect the accuracy of the test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy