Cocaethylene, Urine, Qualitative Screen
This test screens a urine sample for cocaethylene, a substance formed in the body when alcohol and cocaine are used together. It is used to detect recent combined alcohol and cocaine exposure.
["A positive cocaethylene result indicates that cocaine and alcohol were likely used together, since cocaethylene forms only when both are present."]
Key facts at a glance
- LOINC
- 19405-0
- Short code
- Cocaethylene Ur Ql Scn
- Synonyms
- Cocaethylene Ur Ql Scn
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- screen
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Is Cocaethylene
Cocaethylene is a compound that the body produces when cocaine and alcohol are consumed at the same time. It is not present in either substance alone, so its detection is considered a marker of combined use. It is chemically related to cocaine and can be detected in urine after such combined exposure.
How the Test Works
A urine sample is collected and analyzed with a screening method designed to detect the presence of cocaethylene. Screening tests give a preliminary result, and a positive screen may be followed by a more specific confirmatory method to verify the finding. The test is qualitative, meaning it reports whether cocaethylene is detected rather than an exact amount.
What a Positive Result Means
A positive result suggests that cocaine and alcohol were used together within the detection window of the test. Because results can be affected by factors such as how recently substances were used and how the sample was handled, positive screens are typically confirmed with a second, more definitive method before being acted upon.
What a Negative Result Means
A negative result means cocaethylene was not detected in the sample at the test's level of detection. This generally indicates no recent combined alcohol and cocaine use, but it does not rule out use that occurred outside the detection window or use of one substance without the other.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Cocaethylene Urine Screen
Frequently asked questions
Can cocaethylene be detected if only cocaine was used?
How long after use can cocaethylene be found in urine?
Does a screening result need confirmation?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy