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Cocaine Substance Involvement Screening Score

Published: August 9, 2026Updated: August 17, 2026

This test evaluates the likelihood of recent cocaine use based on a combination of factors, including drug screening results and clinical assessment. It helps healthcare providers determine if further testing or intervention may be needed.

Quick summary

["This score helps doctors assess whether cocaine use might be affecting you right now."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
95504-7
Short code
COCAINESUBSTANCEINVOLVEMENTSCORE
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nida
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test combines results from a drug screening test (often a urine or saliva test) with other clinical information, such as symptoms or medical history. It uses a scoring system to estimate the probability of recent cocaine exposure. This is not a direct measurement of cocaine itself but an indirect assessment based on test results and patient factors.

What to Expect Before the Test

You may be asked to provide a urine or saliva sample, depending on the test type. If using urine, avoid certain medications or substances (like some painkillers or vitamins) that could interfere with results. If using saliva, avoid eating or drinking for a short time before testing. Follow any specific instructions your healthcare provider gives you.

What the Test Results Mean

The score does not provide a definitive answer about cocaine use but gives a relative risk assessment. A higher score suggests a greater likelihood of recent use, while a lower score may indicate less recent exposure. This score is used alongside other clinical judgment and may prompt additional testing or support services.

Clinical Significance

This screening score helps healthcare providers identify patients who may benefit from further evaluation, counseling, or treatment for substance use. It can also guide decisions about whether to recommend abstinence, monitoring, or support programs. Results should always be interpreted in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cocaine screening scores are not diagnostic on their own but are part of a broader approach to assess substance involvement. They are commonly used in clinical settings to identify patients who may need additional support or interventions related to substance use.

Short name

Cocaine Screening Score

Frequently asked questions

Why might I need this test?
Your doctor may order this test if they suspect recent cocaine use based on symptoms, medical history, or other factors. It helps them determine the best next steps for your care, such as further testing or connecting you with support services.
What does a high or low score mean?
A high score suggests a greater chance of recent cocaine exposure, but it doesn’t confirm use. A low score means the likelihood is lower, but it doesn’t rule out use entirely. Your doctor will discuss the results with you and explain how they fit into your overall care plan.
Can I affect the score before the test?
Yes, certain actions—like avoiding certain medications, foods, or substances—can influence test results. Follow your doctor’s instructions carefully to ensure the most accurate assessment. Avoiding alcohol, nicotine, or other drugs that could interfere with screening tests is also important.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy