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Cocaine metabolite screening in serum/plasma (e.g., benzoylecgonine)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of cocaine and its breakdown products in your blood, often used to assess recent drug use.

Quick summary

["Detects cocaine exposure for medical or legal purposes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111055-0
Short code
Cocaine Msmt SerPl
Synonyms
Cocaine Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’ve been exposed to cocaine, if you’re suspected of drug use, or as part of a routine screening (e.g., workplace, legal, or pre-employment). It helps monitor your health if you’re using cocaine or managing withdrawal symptoms.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein to draw blood. If you’re nervous, let your provider know—they can help make it more comfortable.

What the Test Results Mean

Results show whether cocaine or its metabolites are present. High levels may indicate recent use, but they don’t confirm the exact time or amount. Always discuss results with your provider.

Common Uses and Limitations

This test is often used for screening but isn’t definitive for diagnosing cocaine use alone. Other tests (like urine drug screens) may be needed for confirmation. False positives can occur with certain medications or other substances.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cocaine metabolites

Frequently asked questions

Will this test show if I’ve used cocaine recently?
Yes, but results depend on how recently you used it. Cocaine breaks down into metabolites (like benzoylecgonine) that stay in your system for hours to days. Your provider will consider the timing and other factors when reviewing results.
Can I drink alcohol before this test?
No restrictions are typically given for this test, but alcohol can sometimes affect blood tests. If you’re unsure, ask your provider about any potential interactions.
What if my results are positive?
A positive result means cocaine or its metabolites were detected. Your provider will discuss next steps, such as follow-up tests, treatment options, or support resources based on your situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy