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Cocaine metabolite screening (24-hour urine)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of cocaine metabolites in your urine over a 24-hour period to detect recent cocaine use.

Quick summary

["Detects recent cocaine exposure through urine analysis over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111229-1
Short code
Cocaine Msmt Ur
Synonyms
Cocaine Msmt Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of cocaine use, such as rapid heartbeat, anxiety, or trouble sleeping. It could also be part of a routine screening, pre-employment check, or legal requirement. Some people take this test to monitor substance use before treatment begins or to check for drug use in certain settings like work or school.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample in a private area. If this is part of a workplace or legal screening, follow any specific instructions your employer or organization provides. Avoid drinking excessive water before the test, as it may dilute the sample.

What the Test Results Mean

Positive results indicate recent cocaine use, while negative results suggest no detectable cocaine metabolites in your urine over the past 24 hours. However, results alone don’t confirm the exact amount or timing of use. Follow-up testing or additional questions may be needed for a full assessment.

Possible Risks and Considerations

There are no major risks associated with this test. However, false positives can sometimes occur due to other substances or medications. If you’re unsure about your medical history or taking other drugs, let your healthcare provider know to avoid confusion in results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps identify recent cocaine exposure, which can guide treatment decisions, monitor substance use disorders, or assess compliance with treatment plans. It’s also used in legal contexts to determine drug use. However, results should always be interpreted alongside clinical judgment and patient history.

Short name

None

Frequently asked questions

What does a positive result mean?
A positive result means your urine contains detectable levels of cocaine metabolites, suggesting recent use. This doesn’t confirm the exact amount or duration of use, but it signals potential exposure that may need further evaluation.
Can false positives happen?
Yes, false positives can occur due to other drugs, medications, or even certain foods. If your results are positive, your healthcare provider may order additional tests to clarify the cause.
How soon after use will the test show results?
Cocaine metabolites typically appear in urine within a few hours of use and can remain detectable for up to 24 hours, depending on individual metabolism. This test captures the full 24-hour window to provide a comprehensive picture.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy