Skip to content

Cocaine metabolite screening (qualitative, urine)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of cocaine metabolites in your urine, often used to screen for recent cocaine use.

Quick summary

["A simple urine test to check for recent cocaine exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110331-6
Short code
Cocaine Msmt Usub
Synonyms
Cocaine Msmt Usub
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of cocaine use, such as anxiety, rapid heartbeat, or trouble sleeping. It can also be part of a routine screening for substance use, especially in certain settings like workplaces, schools, or before certain medical procedures.

What to Expect Before the Test

You’ll likely be asked to provide a urine sample in a private area. No special preparation is needed, but avoid drinking excessive fluids before the test. If you’re pregnant, breastfeeding, or have a medical condition, tell your provider before testing.

What the Test Results Mean

A positive result means cocaine metabolites were found in your urine, suggesting recent use. A negative result means no detectable metabolites were found. However, false negatives can occur if the test was taken too early after use. Results are qualitative (yes/no) rather than quantitative.

What to Do If Your Results Are Positive

If your test is positive, your provider will discuss next steps, which may include follow-up tests, counseling, or treatment options. Avoid using cocaine or other substances while waiting for further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps identify recent cocaine exposure and can guide treatment decisions, especially in cases of suspected substance abuse. It’s not a definitive diagnosis but can prompt further investigation or support services. False positives can occur with certain medications or other drugs.

Short name

Urine Cocaine Screen

Frequently asked questions

How soon after using cocaine can this test detect it?
Cocaine metabolites typically appear in urine within 2–4 hours after use and may remain detectable for up to 3–5 days, depending on individual metabolism.
Can I drink alcohol before this test?
Alcohol itself won’t interfere with the test, but excessive fluid intake may dilute your urine. Avoid heavy drinking if your provider has specific instructions.
What if I take certain medications or use other drugs?
Some medications or other drugs (like certain antidepressants or stimulants) may cause false positives. If you’re unsure, tell your provider about all medications or substances you’ve used recently.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy