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Cocaine concentration in urine (24-hour urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cocaine present in your urine over a 24-hour period, often used to detect recent drug use.

Quick summary

["Detects recent cocaine exposure via urine sample over a full day’s timeline."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53747-2
Short code
Cocaine Pnl Ur
Synonyms
Cocaine Pnl Ur
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Cocaine is a powerful stimulant that can affect your heart, brain, and nervous system. Detecting its presence in your urine helps healthcare providers understand if you’ve recently used cocaine, which may be important for treatment planning or safety reasons. This test is commonly used in medical, legal, or workplace settings to screen for substance use.

How the Test Works

Your urine is collected over a 24-hour period and tested for cocaine metabolites. These metabolites are chemical byproducts of cocaine that remain in your body after use. The test measures their concentration, which can indicate whether cocaine was present in your system during that time.

Sample Collection

You’ll need to collect all urine produced in a 24-hour period (typically from one morning to the next morning) into a special container. Some facilities may provide a timed collection kit to ensure accuracy. It’s important to follow instructions carefully to get reliable results.

What to Expect Before the Test

There are no special preparations needed for this test. However, if you’re taking certain medications or have health conditions, let your healthcare provider know. Avoid drinking excessive amounts of fluids before the test, as this could dilute the urine and affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Cocaine Screen

Frequently asked questions

What does a positive result mean?
A positive result means that cocaine metabolites were detected in your urine over the 24-hour period. This typically indicates recent use of cocaine, but it doesn’t specify the exact amount or timing of use. Healthcare providers may use this information to guide further evaluation or treatment plans.
Can I still use cocaine after the test starts but before it’s complete?
No, it’s important to avoid using cocaine during the 24-hour collection period. Cocaine and its metabolites can remain in your system for several days, so using it later could still affect the results. If you’re unsure about your recent use, it’s best to discuss this with your healthcare provider.
Will my results be affected if I drink a lot of water before the test?
Drinking excessive amounts of water before the test could dilute your urine and potentially affect the accuracy of the test. Follow your healthcare provider’s instructions for fluid intake to ensure reliable results. Some facilities may provide specific guidelines to help you prepare properly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy