Cocaine concentration in urine (24-hour urine collection)
This test measures the amount of cocaine present in your urine over a 24-hour period, often used to detect recent drug use.
["Detects recent cocaine exposure via urine sample over a full day’s timeline."]
Key facts at a glance
- LOINC
- 53747-2
- Short code
- Cocaine Pnl Ur
- Synonyms
- Cocaine Pnl Ur
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Cocaine is a powerful stimulant that can affect your heart, brain, and nervous system. Detecting its presence in your urine helps healthcare providers understand if you’ve recently used cocaine, which may be important for treatment planning or safety reasons. This test is commonly used in medical, legal, or workplace settings to screen for substance use.
How the Test Works
Your urine is collected over a 24-hour period and tested for cocaine metabolites. These metabolites are chemical byproducts of cocaine that remain in your body after use. The test measures their concentration, which can indicate whether cocaine was present in your system during that time.
Sample Collection
You’ll need to collect all urine produced in a 24-hour period (typically from one morning to the next morning) into a special container. Some facilities may provide a timed collection kit to ensure accuracy. It’s important to follow instructions carefully to get reliable results.
What to Expect Before the Test
There are no special preparations needed for this test. However, if you’re taking certain medications or have health conditions, let your healthcare provider know. Avoid drinking excessive amounts of fluids before the test, as this could dilute the urine and affect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
24-Hour Urine Cocaine Screen
Frequently asked questions
What does a positive result mean?
Can I still use cocaine after the test starts but before it’s complete?
Will my results be affected if I drink a lot of water before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy