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Cocaine concentration in serum/plasma (quantitative measurement)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cocaine in your blood, often checked if you suspect drug use or exposure.

Quick summary

["Cocaine levels help doctors assess risk, guide treatment, or monitor recent use."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3395-1
Short code
Cocaine SerPl Ql
Synonyms
Cocaine SerPl Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’ve had symptoms like rapid heartbeat, confusion, or unusual behavior that could be linked to cocaine use. It may also be used in emergency settings for suspected overdose or during investigations like workplace drug testing or legal proceedings.

How the Test Works

A small blood sample is taken from a vein in your arm. The sample is then analyzed using a specialized immunoassay method to detect cocaine and its metabolites (chemical breakdown products) in your bloodstream.

What to Expect Before the Test

No special preparation is needed, but inform your provider if you’re taking medications that might affect blood tests or if you have a history of bleeding disorders.

What to Expect During the Test

You’ll lie down comfortably while a nurse inserts a needle into your vein. You may feel a brief pinch, but the procedure usually takes only a few minutes. You’ll be able to sit or lie down afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate recent cocaine exposure, which can impact heart health, blood pressure, and mental well-being. High levels may require immediate medical attention, especially if symptoms like chest pain or seizures occur. Results help tailor treatment plans, such as detoxification or support for addiction.

Short name

Cocaine Level (Screen/Confirm)

Frequently asked questions

How long does it take to get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your provider will contact you directly with the outcome.
Can I drink alcohol before this test?
Alcohol itself won’t interfere with the test, but it may affect your overall health if combined with cocaine use. Follow your provider’s advice on any restrictions.
What if my test is positive for cocaine?
A positive result means cocaine was detected in your blood. Your provider will discuss next steps, which may include medical evaluation, counseling, or treatment options based on your health and situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy