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Cocaine Substance Concentration in Serum/Plasma (Screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of cocaine or its metabolites in your blood, helping detect recent use.

Quick summary

["A simple blood test to check for recent cocaine exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8190-1
Short code
Cocaine SerPl Ql Cfm
Synonyms
Cocaine SerPl Ql Cfm
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects cocaine and its active metabolites (such as benzoylecgonine) in your blood. It’s typically used to screen for recent cocaine use, often in clinical, forensic, or occupational settings.

Why You Might Need This Test

Your healthcare provider may order this test if you’ve been exposed to cocaine, if symptoms like confusion, rapid heartbeat, or altered mood are present, or as part of a routine screening (e.g., pre-employment, legal, or substance use assessment).

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein to draw blood. If you’re nervous, let your provider know—they can offer comfort measures.

What to Expect After the Test

You’ll likely feel a brief pinch or discomfort at the injection site. Most people recover quickly, but if you experience bruising or pain, apply gentle pressure to the area or take an over-the-counter pain reliever as needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cocaine Screen (Serum/Plasma)

Frequently asked questions

How long does it take to get results?
Results are usually available within 1–2 business days, depending on your lab’s processing time. Your provider will contact you once they’re ready.
Can I drink alcohol before this test?
No, avoid alcohol for 24 hours before testing, as it may interfere with the test’s accuracy.
What if my results are positive?
A positive result means cocaine or its metabolites were detected in your blood. Your provider will discuss next steps, which may include further testing, counseling, or treatment options tailored to your needs.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy