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Cocaine concentration in serum/plasma (qualitative or quantitative screening/confirmation)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of cocaine in your blood, either as a screening or confirmation test to detect recent use.

Quick summary

["Detects recent cocaine exposure through blood analysis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8191-9
Short code
Cocaine SerPl Ql Scn
Synonyms
Cocaine SerPl Ql Scn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like rapid heartbeat, confusion, or unusual behavior that could be linked to cocaine use, or if you’re suspected of recent drug exposure in a medical or legal context.

What to Expect During the Test

You’ll have a small needle inserted into your arm to draw blood. The sample is then sent to a lab for analysis. Results may be qualitative (yes/no) or quantitative (specific amount detected).

What the Results Mean

A positive result indicates recent cocaine exposure, but it doesn’t confirm ongoing use. Levels can vary based on timing since last use, dose, and metabolism. Follow-up testing may be needed for further evaluation.

Common Reasons for Testing

This test is often used in emergency settings, workplace drug screens, or legal investigations where recent drug use is suspected.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cocaine in Serum/Plasma

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Some urgent cases may receive results sooner.
Can I eat or drink before this test?
Standard fasting rules may apply for blood draws, but confirm with your provider. Generally, avoid heavy meals or alcohol before testing.
Does this test detect other drugs?
No, this test specifically measures cocaine metabolites. Other drug screens may be needed to identify additional substances.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy