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Coccidioides antibody, serum/plasma (qualitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to *Coccidioides* fungi, which can cause infections like Valley Fever. Antibodies appear in your blood after exposure.

Quick summary

["This screening helps detect past or current exposure to *Coccidioides* fungi."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49190-2
Short code
Coccidioides Ab Fld Ql
Synonyms
Coccidioides Ab Fld Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects the presence of antibodies against *Coccidioides* organisms in your blood. Antibodies are proteins your immune system makes in response to infection. A positive result suggests you may have been exposed to the fungus, though not everyone exposed will test positive.

Why Might You Need This Test?

Healthcare providers may order this test if you live in or have traveled to areas where *Coccidioides* is common (e.g., parts of the southwestern U.S.), have symptoms like fever, cough, or fatigue, or have conditions that make you more vulnerable to infections.

What Does a Positive Result Mean?

A positive result means your body has detected antibodies to *Coccidioides*, indicating past or possible current exposure. This does not always mean you have an active infection, but it warrants further evaluation by a healthcare provider.

What Does a Negative Result Mean?

A negative result means your body did not detect antibodies to *Coccidioides* at the time of testing. This could mean you have never been exposed or that your immune system hasn’t yet produced detectable antibodies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Coccidioides Antibody Screen

Frequently asked questions

How is this test performed?
This is a blood test. A small sample of your serum or plasma is collected via a vein in your arm. The test checks for antibodies using an immunoassay method, which detects specific proteins in your blood.
What are the common symptoms of *Coccidioides* infection?
Common symptoms include flu-like illness (fever, chills, fatigue), cough, chest pain, or skin rashes. Some people may have no symptoms at all, especially if their immune system is strong.
Do I need to prepare for this test?
No special preparation is needed. You may eat or drink as usual before the test, but avoid alcohol for 24 hours if possible.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy