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: Coccidioides immitis/posadasii Antibody Panel, Serum

Published: August 9, 2026Updated: August 16, 2026

: This panel measures antibodies against Coccidioides, the fungus that causes Valley fever, in a blood serum sample to help determine whether you have been exposed to or are infected by this organism.

Quick summary

[": A Coccidioides antibody panel helps detect the body's immune response to the fungus that causes Valley fever."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97521-9
Short code
Coccidioides Ab Patrn Spec ID
Synonyms
Coccidioides Ab Patrn Spec ID
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-diffusion
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Test Measures

: The test looks for antibodies your immune system produces in response to Coccidioides fungi (Coccidioides immitis and Coccidioides posadasii). Antibodies are proteins made by the immune system when it encounters an infection. Detecting them in serum can suggest recent or past exposure to the fungus.

: Why It Is Ordered

: A healthcare provider may order this panel when a person has symptoms of Valley fever, such as fever, cough, chest pain, fatigue, or a rash, especially after living in or traveling to areas where the fungus is common, such as the southwestern United States. It can also help evaluate unexplained respiratory illness.

: How the Sample Is Collected

: The test uses a serum sample, which is the clear liquid part of blood obtained after a blood draw. A healthcare professional collects blood from a vein in your arm, and the sample is sent to a laboratory for analysis.

: What the Results Mean

: Results are typically reported as positive or negative, sometimes with antibody levels or types. A positive result may indicate exposure to or infection with Coccidioides, while a negative result does not always rule out infection. Your provider interprets results alongside your symptoms, history, and other tests. This test does not provide a specific numeric reference range.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: Coccidioides Antibody Panel

Frequently asked questions

: Do I need to fast before this test?
: No fasting is generally required for a Coccidioides antibody panel. Follow any specific instructions your healthcare provider gives you.
: Can a negative result mean I do not have Valley fever?
: Not necessarily. Antibodies may take time to appear, and a negative result does not completely rule out infection. Your provider will consider your symptoms, exposure history, and other tests.
: Is this test the same as a fungal culture?
: No. This panel detects antibodies your body makes against the fungus. A fungal culture or other direct detection methods look for the organism itself and may be used together with antibody testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy