Coccidioides antibody serologic test (qualitative or semiquantitative)
This test detects antibodies in your blood that may indicate exposure to *Coccidioides* fungi, commonly found in certain desert regions. It helps diagnose coccidioidomycosis, a fungal infection that can affect the lungs and sometimes spread to other parts of the body.
["This test helps identify possible fungal exposure and infection risk, especially in areas where the fungus is prevalent."]
Key facts at a glance
- LOINC
- 33381-5
- Short code
- Coccidioides Ab Ser-aCnc
- Synonyms
- Coccidioides Ab Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you live in or have traveled to regions with high risk for *Coccidioides* exposure, such as parts of the southwestern United States, Central and South America, or Australia. It may also be used after an illness that could be caused by fungal infection, such as pneumonia or skin rashes.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process is quick and typically painless. If you’re pregnant or have a bleeding disorder, let your provider know before the test.
What the Test Results Mean
Results are qualitative (positive/negative) or semiquantitative (showing relative antibody levels). A positive result suggests past or current exposure to the fungus, but it doesn’t always mean you’re sick. False positives can occur, so follow-up testing may be needed.
Possible Side Effects
Most people experience mild discomfort or bruising at the injection site. Rarely, there may be a slight reaction like redness or swelling. If you develop a fever, chills, or severe pain, contact your provider immediately.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Coccidioides antibody screening/confirmation
Frequently asked questions
A positive test result may prompt further evaluation, including additional testing to confirm infection or rule out other conditions. It’s important for monitoring long-term health if you’ve had exposure or symptoms. Early detection can help guide treatment decisions.
Can this test be used to diagnose active infection?
What should I do if I have a positive result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy