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Coccidioides antibody serology (qualitative, serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that your immune system produces in response to *Coccidioides* (a fungal infection). It helps identify if you’ve been exposed to the fungus, which can cause illness in some people.

Quick summary

["This test helps doctors assess possible exposure to a fungal infection that may require further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26625-4
Short code
Coccidioides Ab Ser Ql
Synonyms
Coccidioides Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, cough, chest pain, or fatigue—especially if you live in or traveled to areas where *Coccidioides* is common, such as parts of the southwestern U.S., Central/South America, or Australia. They might also recommend it if you have a weakened immune system or a history of similar infections.

What to Expect During the Test

A small blood sample is taken from a vein in your arm. The sample is sent to a lab for testing. Results are qualitative (positive/negative) rather than a specific measurement.

What the Results Mean

A **positive** result means your body has detected antibodies to *Coccidioides*, suggesting past or current exposure. A **negative** result means no detectable antibodies were found, but this doesn’t always rule out exposure. Follow-up testing or additional questions may be needed.

Possible Next Steps

If your result is positive, your doctor may order further tests (like a *Coccidioides* antigen test) or recommend monitoring for symptoms. If symptoms develop, they may prescribe treatment to manage infection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Coccidioides Antibody Screen

Frequently asked questions

What does a positive result mean for my health?
A positive result indicates your immune system has responded to *Coccidioides*, which can cause mild to severe illness. It doesn’t always mean you’re currently sick, but it may prompt further evaluation to assess risk or need for treatment.
Can a negative result mean I’m not infected?
No. A negative result means no antibodies were detected in this test, but you could still be infected or exposed. Some people don’t develop detectable antibodies, so repeat testing or other diagnostic methods may be needed.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the results with you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy