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Coccidioides antibody serologic test (qualitative, serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that may indicate exposure to *Coccidioides* fungi, which can cause infections like Valley Fever.

Quick summary

["A positive result suggests possible exposure to the fungus, often linked to respiratory symptoms or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43052-0
Short code
Coccidioides Ab Spec Ql
Synonyms
Coccidioides Ab Spec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test identifies the presence of antibodies produced by your immune system in response to exposure to *Coccidioides* organisms. Antibodies are proteins your body makes to fight infections, and their detection helps determine if you’ve been exposed to the fungus, which can live in soil in certain regions.

Why It’s Ordered

Your healthcare provider may order this test if you live in or have traveled to areas with high risk for Valley Fever (e.g., parts of the southwestern U.S.), have symptoms like cough, fever, or fatigue, or if you have a weakened immune system.

Symptoms It May Help Identify

A positive antibody result doesn’t always mean you’re currently sick, but it can signal past exposure. Symptoms of an active infection may include flu-like illness, chest pain, or persistent cough, especially if you’ve had recent travel or exposure to dusty environments.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is quick and typically done in a lab setting.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Coccidioides antibody screen

Frequently asked questions

This test helps diagnose or rule out *Coccidioides* infection, which can range from mild respiratory issues to severe complications in some cases. Antibody levels may change over time, so follow-up testing may be recommended if symptoms persist or worsen.
A positive result means your immune system has detected the fungus, but it doesn’t confirm an active infection. Further testing (like cultures or additional antibody titers) may be needed to assess severity or guide treatment.
Does this test show if I have an active infection?
No, this test only detects antibodies, which indicate past or possible exposure. Active infection would require additional tests, such as cultures or specialized antibody assays.
Can I get this test at home?
No, this is a blood test typically done in a clinical lab. Your provider will arrange for a sample to be collected at a healthcare facility.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy