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Coccidioides antibody serologic test (qualitative, serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that may indicate exposure to *Coccidioides* (a fungal infection also called Valley Fever). It helps doctors assess risk or diagnose potential infection.

Quick summary

["Identifies possible exposure to Valley Fever fungus through antibody presence."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31153-0
Short code
Coccidioides Ab Spec Ql ID
Synonyms
Coccidioides Ab Spec Ql ID
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-diffusion
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’ve lived in or traveled to regions where Valley Fever is common (e.g., parts of the southwestern U.S., Central/South America), have symptoms like fever, cough, or fatigue, or have risk factors such as weakened immunity.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample (usually drawn from your arm) in a lab. Results are qualitative (positive/negative) rather than a specific number.

What the Test Results Mean

A positive result suggests your immune system has detected *Coccidioides* antibodies, possibly from past exposure. A negative result means no detectable antibodies at this time, but exposure could still have occurred without symptoms.

Possible Symptoms Linked to Exposure

Exposure to *Coccidioides* can cause mild flu-like symptoms (e.g., cough, headache) or, in rare cases, severe lung infections or other complications. Symptoms may appear weeks to months after exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Coccidioides Antibody Screen/Consolidated

Frequently asked questions

What does a positive result mean?
A positive result means your body has produced antibodies against *Coccidioides*, which could indicate past exposure. It doesn’t confirm active infection—your doctor will assess symptoms and other tests to determine next steps.
Can I get Valley Fever from this test?
No, this test doesn’t transmit the fungus. It only detects your immune response to it. If you suspect exposure, consult your doctor about preventive measures or treatment options.
How often should I get retested?
Only your doctor will determine if retesting is needed. They may recommend follow-ups if you have symptoms, a weakened immune system, or live in a high-risk area. Results are typically valid for monitoring trends over time, not as a one-time check.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy